BDKRB2 anticorps (C-Term)

N° du produit ABIN4886484

Cet anticorps anti-BDKRB2 est un anticorps Lapin Polyclonal détectant BDKRB2 dans WB. Adapté pour Humain.

Aperçu rapide pour BDKRB2 anticorps (C-Term) (ABIN4886484)

Antigène: BDKRB2 (Bradykinin Receptor B2 (BDKRB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BDKRB2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BDKRB2 anticorps

Épitope: AA 357-391, C-Term

Fonction: Anti-BDKRB2 Antibody Picoband®

Séquence: RSEPIQMENS MGTLRTSISV ERQIHKLQDW AGSRQ

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-BDKRB2 Antibody Picoband® (ABIN4886484). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human BDKRB2, different from the related mouse sequence by five amino acids, and from the related rat sequence by seven amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human
1. Fernandes L, Fortes ZB, Nigro D, Tostes RC, Santos RA, Catelli De Carvalho MH (2001). "Potentiation of bradykinin by angiotensin-(1-7) on arterioles of spontaneously hypertensive rats studied in vivo".Hypertension 37 (2 Part 2): 703-9. 2. Hess JF, Borkowski JA, Young GS, et al. (1992). "Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor.". Biochem. Biophys. Res. Commun. 184 (1): 260-8.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur BDKRB2

Antigène: BDKRB2 (Bradykinin Receptor B2 (BDKRB2))

Autre désignation: BDKRB2

Sujet:

Synonyms: B2 bradykinin receptor,B2R,BK-2 receptor,BDKRB2,BKR2,

Tissue Specificity: Ubiquitous. Widespread in normal smooth muscle tissue and neurons. .

Background: Bradykinin receptor B2 is a G-protein coupled receptor forbradykinin, encoded by the BDKRB2 gene in humans. This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein.

Poids moléculaire: 50 kDa

ID gène: 624

UniProt: P30411

Pathways: ACE Inhibitor Pathway, Negative Regulation of intrinsic apoptotic Signaling